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Penicillin Allergy Management: Removing Barriers to Optimal Antibiotic Prescribing
In current practice, penicillin allergy labels are largely unevaluated and untested. Penicillin allergy labels present a barrier to optimal antibiotic prescribing. After an evaluation, most such labels will be low risk and can be safely challenged with a dose of amoxicillin to disprove and remove the allergy. In this interactive course, learners will gain experience in penicillin allergy history taking, risk assessment using validated instruments, penicillin allergy testing, and delabeling.
Topics Covered:
- Module 1: Learn about penicillin allergies: What are the adverse effects, how to take a history and perform a risk assessment
- Module 2: Learn about penicillin allergy testing: When to test, how to test, and how to delabel
- Module 3: Learn about penicillin allergy teamwork: How to engage patients, how to document penicillin allergy testing, and how to function as a team
Target Audience
Healthcare providers managing patients with penicillin allergy labels, including physicians (ID, PCP, hospitalists), pharmacists, and advanced practice providers.
Learning Objectives
At the end of this activity, learners should be able to:
- Acknowledge the critical impact of assessing penicillin allergies on enhancing patient treatment outcomes and fostering responsible antimicrobial medication usage.
- Master the process of conducting a thorough history centered on penicillin allergies and conducting risk assessments using validated methods.
- Recognize the importance of a patient's penicillin allergy risk assessment in guiding testing decisions and determining the suitability of prescribing cephalosporin antibiotics.
- Demonstrate the ability to conduct an amoxicillin challenge for patients with low-risk penicillin allergies.
- Define the importance of penicillin allergy skin testing as a preliminary assessment for higher-risk patients before challenges.
- Identify the significance of avoiding beta-lactams in cases of severe delayed allergic reactions and provide a descriptive understanding of appropriate strategies for patient care.
- Define key communication principles for effectively involving patients in the process of penicillin allergy de-labeling
- Acquire the skills to accurately document successful allergy challenges and develop the ability to counsel patients on the significance of being de-labeled from penicillin allergy.
- Develop strategies for engaging with hospital steering, pharmacy, and therapeutics committees to enhance the management of penicillin allergies within the healthcare system.
- Identify the components and skills of a multidisciplinary healthcare team capable of implementing penicillin allergy delabeling in a variety of healthcare settings.
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Funding for this online educational program was made possible (in part) by the Centers for Disease Control and Prevention. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services, nor does the mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
In accordance with the Accreditation Council for Continuing Medical Education's (ACCME) Standard for Integrity and Independence in Accredited Continuing Education, all faculty and planning partners must disclose all financial relationship(s) with any ineligible company within the prior 24 months for any amount. SHEA identifies and mitigates all conflict of interest prior to delivering the educational activity to learners.
Authors
Cosby Stone, Jr., MD, MPH (Co-Chair)
Vanderbilt University Medical Center
Disclosed no relevant financial relationships
Sarah Kabbani, MD, MSc (Co-Chair)
Division of Healthcare Quality Promotion
Centers for Disease Control and Prevention
Disclosed no relevant financial relationships
Tanaya Bhowmick, MD
Rutgers Robert Wood Johnson Medical School
Disclosed no relevant financial relationships
Rebecca Choudhury, MD
Mount Sinai Queens
Icahn School of Medicine at Mount Sinai
Disclosed no relevant financial relationships
Jumy (Olajumoke) Fadugba, MD, FAAAAI
Penn Medicine
Disclosed no relevant financial relationships
Autumn Guyer, MD
Memorial Sloan Kettering Cancer Center
Disclosed no relevant financial relationships
Jason Trubiano, MBBS, PhD
Austin Health
Melbourne Medical School, University of Melbourne
Disclosed no relevant financial relationships
Melinda Neuhauser, PharmD, MPH
Division of Healthcare Quality Promotion
Centers for Disease Control and Prevention
Disclosed no relevant financial relationships
Jamie Wagner, PharmD, BCIDP
University of Mississippi School of Pharmacy
Disclosed no relevant financial relationships
Rebekah Wrenn, PharmD, BCIDP
Duke University Hospital
Disclosed no relevant financial relationships
All of the authors have no relevant relevant financial relationships.
Accreditation Statements 
In support of improving patient care, The Society for Healthcare Epidemiology of America is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physicians:
The Society for Healthcare Epidemiology of America designates this enduring activity for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
ABIM MOC Recognition Statement
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 2.0 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to Joint Accreditation for the purpose of granting ABIM MOC credit.
By submitting a claim for ABIM MOC, you hereby give SHEA permission to share individual physician participation information with ABIM through JA PARS.
Pharmacists:
CPE Accreditation Statement for Pharmacists
SHEA is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. The Universal Activity Number for this program is UAN JA0006047-0000-24-009-H01-P. This activity is acceptable for a maximum of 2.0 live CPE contact hours (2.0 CEUs) in states that recognize ACPE providers.
Upon completion of this ACPE-approved activity, participants will receive 2.0 credits on their NABP e-Profile section of the CPE Monitor. It is the participant's responsibility to upload the correct NABP number and date of birth when submitting your evaluation.
Disclaimer
The information provided during this CME activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a healthcare professional relative to diagnostic and treatment options of a specific patient's medical condition.
Available Credit
- 2.00 ABIM MOC
- 2.00 ACPE Pharmacy
- 2.00 AMA PRA Category 1 Credit™
- 2.00 Participation
Price
Thank you for your interest in registering for the Penicillin Allergy Management course provided by The Society for Healthcare Epidemiology of America (SHEA). SHEA is a professional society that improves public health by establishing infection-prevention measures and supporting antibiotic stewardship among healthcare personnel. As a first-time user, you will need to create a profile before you can sign up for the course. Once you’re profile has been completed, you’ll be able to complete your registration for this course. If you are already a member, you’ll simply need to log in.
Continuing Education Credits and Certificates:
- Once you pass the post test of each of the modules you wish to complete, you will complete the PROGRAM EVALUATION, claim credits and select your certificate(s).
- You can only claim credits ONCE. Be sure to claim credits AFTER you have completed all desired modules.
- You will be able to print/download the certificate of completion and accreditation certificates for which you opted in.